There is hundreds potentially thousands of issues that the USP fixes that Bethesda themselves never got around to actually fixes themselves. Even if you plan to play Skyrim, even a vanilla playthrough should not be without using the Unofficial Skyrim Patch. You should at least try the original unaltered game first, and then play with mods to appreciate how improved the changes actually are. I think as a fair point if you never played Skyrim before on any platform. There is huge swath of improvements visuals, to the crafting, level environments, new quests, new landmasses to explore, improved gameplay mechanics such as combat overhauls, survival elements, and so forth.
I cannot stand playing Skyrim without mods anymore.